Compared to traditional resin, Magnetic Beads eliminate the need for complex procedures such as column packing. The process is straightforward and offers high purification efficiency, enabling small-scale, high-throughput purification.

rProtein G or rProtein A ligands are densely and oriented immobilized onto magnetic microspheres, enabling antibody purification via Fc-mediated IgG binding. Compared to native proteins, our recombinant ligands feature high-affinity binding sites, thereby minimizing non-specific adsorption.

1. High binding capacity

Under identical conditions, antibodies were purified using resin and magarose beads, respectively. As indicated by the yield(Figure 1.1) and purity(Figure 1.2) of the purified products, the capture and binding capacity of the magnetic beads is highly comparable to that of the resin.

2. High-throughput Application Case

Different sample types (cell culture supernatant and rabbit serum) were incubated with  rProtein A/G MagPoly Beads(Cat:SM01510) for automated purification on the Purifier 24(Cat:P241001). For the cell culture supernatant, parallel experiments were conducted with varying concentrations and volumes. The purity and recovery yield of the purified products were both ≥90%（Table 1, Figure 2).

Table 1 Results of Recovery yield and Purity

Figure 2 Results of Purity( SDS-PAGE)